The drug is only recommended for use in veterinary medicine. It has never been approved for use in humans in North America. Boldenone has come to fame mainly because of its abuse by bodybuilders.

Pharmacology

Boldenone is like many other synthetic steroids. It is a potent anabolic agent at low doses and at high doses possesses both anabolic and androgenic properties. At low doses it can build the body when the diet is rich in calories.  However, because it acts like an anabolic steroid, it can suppress the normal synthesis of testosterone in the testes. This can lead to impairment in spermatogenesis and decrease in libido.

When the drug is taken in high doses, it can also be converted into estrogen which can result in gynecomastia and also leads to water retention.

One other feature of Equipoise is that it can stimulate erythropoiesis (an increase in red blood cells). The mechanism for this effect has been associated with stimulation of the erythropoietin stimulating factor which then stimulates the bone marrow. The resulting increase in red blood cells, leads to more hemoglobin and a higher oxygen carrying capacity. Equipose, like other anabolic steroids can also cause changes in electrolytes because of its potent mineralocorticoid properties.

One major negative of Equipose, unlike its other analogues, is that it can stay in the body for a very long time. It has a prolonged half life because the drug does stay bound to tissues and is not broken down by the liver. Many reports indicate that the drug can be detected as long as 12-15 months after first use.

Bodybuilders

How the drug went from horses to humans is not really known. But the fact is that Boldenone does have potent anabolic activity and low androgenic activity and is useful for building body mass. Boldenone can also cause a significant retention of water and sodium at high doses. Like all anabolic steroids it increases nitrogen balance and protein synthesis. The drug is also known to stimulate the kidney and can release EPO-which then stimulates the synthesis of red blood cell in the bone marrow.

This leads to enhanced oxygen carrying capacity. Even though the drug is only meant for animal use, many bodybuilders routinely use it. The drug is often taken in conjunction with other anabolic steroids. Because of its long half life, many bodybuilders take the drug during off season to avoid detection. The drug is continued for a few months and then stopped when the sports season starts. Boldenone is also a potent appetite stimulant. 

Boldenone does not immediately cause weight gain. It is much slower than many other anabolic steroids. The muscle mass is typically gained over 4-8 weeks and is steady. The majority of bodybuilders notice that the weight gain is more durable and longer lasting after several cycles, with each cycle lasting about 8 weeks. The one great thing about this drug is that the weight gain is pure muscle mass and not related to water.

Boldenone is not a drug one should take during the active sports season. It has a very long half life and is readily detectable in the body. The majority of bodybuilders use it during off season to build up the bulk. Often it is combined with other drugs like Anadrol, Anavar and Sustanol. When the diet is rich in calories, the size of muscles can be impressive.

Dosing

Since the drug has never been approved for human use, the dose of the drug has been derived by simply guess work. Someone has analyzed what horses require than simply extrapolated that dose to humans. The common dose for body building is not known. It varies from 200—800 mg/week. The recommended dose in horses is about 1mg/kg every 2-3 weeks. Most bodybuilders administer about 400mg/week. It is claimed that doses lower than 300mg/week do not help gain weight.

Boldenone is administered as an intramuscular injection. With the formulations available today, it cannot be taken orally. The drug is injected into the buttock area with care. Since the drug comes as an oily suspension, one should not inject more than 4-8 mls at a time. Large volumes of fluid in the buttock area can cause pain and are very uncomfortable. The dose for women bodybuilders is about 50-75 mg/week. If the injections are painful one can inject the drug in 2-3 different sites or change the dosing to 2-3 times a week- same dose but smaller amounts given every other day.

The oily suspension can irritate the skin and it is recommended that the site be rotated every week. Besides the buttocks one can inject the drug into the outer parts of the thighs. The drug is quite painful when injected in the arms.

Side Effects

 Boldenone is an anabolic steroid and has the full spectrum of side effects which include:

Oily skin

Acne

Hair loss

Mood changes- aggression, paranoia, depression

Water retention

Swelling, edema

High blood pressure

Fatigue

Gynecomastia at high doses

Testicular atrophy

Possible liver cancer

Fatique

Unlike other anabolic steroids, the side effects of Boldenone do persist for a long time even after the drug is stopped. Some individuals will continue to have acne and oily skin for months.

Contraindications

While Boldenone is not acutely toxic, the drug is not recommended for use in individuals who

are pregnant

have prostate or breast cancer

have liver problems

have a history of heart disease

renal failure

hypercalcemia

Warnings

All anabolic steroids come with a warning that they have the potential to cause damage to your liver, decrease libido and shrink your testes. There are numerous reports that prolonged intake of boldenone can lead to severe alterations in sexual behavior and spontaneous changes with mood. Aggression and violent behavior have been widely reported after the use of most anabolic steroids.

Over dosage

Like most anabolic steroids, over dosage is very unlikely with boldenone. Even if someone took many pills at the same time, the major problem would be nausea, vomiting or abdominal cramping. In any case, the individual should go to the hospital for monitoring and supportive care. Since all anabolic steroids can damage the liver, measurement of liver enzymes is essential.

Contaminants

The very lucrative anabolic steroid market has led to many unscrupulous sellers, esp. on the internet selling fraudulent steroids. Since the drug is only available on the black market, many consumers have no recourse even if they know they have been suckered into buying a counterfeit or fake product. And there are lots of reports of counterfeit or contaminated Boldenone formulations. In the USA, the boldenone is smuggled in from Mexico, Japan, Thailand and South America. Once upon a time there were tablets of 25 and 50 mg available as well as liquid formulations of 50 cc vials. However, it is now evident that the tablets were not Boldenone but a mixture of other steroids. The price for 10 mls vial (50mg/ml) averages about $50-$75. Because of the fake products and contamination, always get your drug from a reputable dealer. The cyberspace is full of charlatans who will sell you junk because they do know you can’t go and complain to anyone about the product they sell you.

Control

Boldenone is not for use in humans and the FDA has classified this drug under the Controlled Substance Act as a Schedule 3 drug. The drug is unlawful to possess, distribute or for personal use.

Detection

Boldenone has a very long half life and can remain in the body for months or even years. The oily emulsion has an affinity for fatty tissues and resides in the body for months. The metabolites of boldenone have been found in urine 12 months after the last injection. So one has to have a plan before shooting this drug. If you are going to enter a competition in the next few months, boldenone is the last drug you should inject. It is best reserved for the novice athlete who is just starting out and wants to build his/her body. Further one must not anticipate engaging in sports for that time period. Every sporting organization has banned the use of the drug and it is always checked in the urine. The tests available can identify boldenone and its metabolites.

Alternative designation

bold, bolde, bolden, boldene, boldeno, boldenon, boldenone, bold 250, bolde 250, genesis, undecylenat, undecylenate, march, boldo, boldoj, boldoje, boldojec, boldoject, boldoject 200, ec, euroche, eurochem, equipois, equipoise, equipoise 250, maxpro, vebol, vebold, vebolde, veboldex, veboldex 250, thaiger pharma, x-bold, x-bolde, x-bolden, x-boldeno, x-boldenon, x boldenon, extrem, extreme, ganabol, ultragan, Boldane, Boldebal-H, Equipoise, Ganabol, Pace, Parenabol, Sybolin, Vebonol

L'articolo Boldenone Undecylenate March 1ml amp [200mg/1ml] proviene da Steroids.TO.

The testosterone is esterified and thus is quite long acting. It is only available in an injection form. The anabolic steroid is typically dissolved in sesame or cotton seed oil and injected into the buttock area. The drug is slowly released from the injection site for about 7-12 days.    

The formulation comes as white milky powder and is insoluble in water but freely soluble in most organic solvents including vegetable oil.

Pharmacology

The body normally makes sex hormones like testosterone which is responsible for the normal growth and development of the secondary sexual features. This includes growth of the prostate, testes, penis, scrotum, body hair, vocal cord thickening, alterations in body fat and musculature. When testosterone deficiency occurs, the secondary sexual characteristics and body growth is always abnormal. Thus, one of the indications of testosterone therapy is in the treatment of individuals who lack testosterone or are infertile.

Indications for use

Testosterone Cypionate is used to treat conditions in made where there is a failure of testosterone to be secreted like:
     
primary failure of the testes to make the hormone
failure of the pituitary to release Gonadotropins

Body building

Testosterone and its analogues are widely used by athletes and bodybuilders. The steroid is taken principally to enhance the body and stimulate the psyche. Most bodybuilders who take this drug claim that it causes spontaneous bursts in energy associated with increased aggression. This feature of the drug is used primarily by weight lifters and professional wrestlers. Many athletes also claim that the drug improves their ability to perform exercise at intense levels.
 
Testosterone has moderate anabolic properties but also is a powerful androgenic agent.
 
Because the drug is given by an injection, its effects on the body are not rapid. One may not see any effects for at least 3-4 weeks after starting the injections. Unlike the oral testosterone, the injected formulations last a longer in the body.
 
When taken for more than 4-6 weeks, it can increase body mass and protein anabolism. However, for the body to build muscle one also has to eat a diet rich in calories. Most bodybuilders also take a combination of other hormones at the same time. Because testosterone is converted to estrogen in the fatty tissues, there is always the chance of developing gynecomastia and water retention. To prevent this, most bodybuilders add Arimidex or tamoxifen during the off cycle.
 
During testosterone injections, the natural body testosterone release is inhibited by feedback mechanism through inhibition of pituitary LH. At large doses, even spermatogenesis can be impaired. To allow for the hypothalamic-pituitary axis to recover, it is highly recommended that the drug be tapered off slowly over a period of a few weeks. Sudden discontinuation of the drug can lead to extreme fatigue, weight loss and susceptibility to fractures.

Contraindications

There are some individuals who should avoid testosterone like steroids because it can worsen the clinical condition. These conditions include:
     
those with allergy to the drug
males with breast cancer
males with prostate cancer
Women who are pregnant or breast feeding
Individuals who have liver, kidney or heart problems

Side Effects

When Testosterone Cypionate is injected at low doses, the side effects are rare. However, long term use is known to be associated with a varied number of side effects – all of which are reversible when the drug is stopped. For the female who decides to take testosterone, there are virilizing side effects which are not always reversible when the drug is stopped. Like all anabolic steroids, testosterone also has a number of side effects which includes:
     
nausea, vomiting
abdominal cramps, diarrhea
swelling
ncreased /decreased libido
headaches
acne, oily skin
mental change including anger, depression, insomnia
diaphoresis
loss of hair
gynecomastia
 
When taken by females, the drug definitely can cause virilizing effects like:
     
deepening of voice
hoarseness
excess hair growth
enlarged clitoris
irregular menstrual cycles
 
Testosterone Cypionate is converted into estrogen in the fatty tissues. The estrogen than leads to development of breast enlargement and water retention. This effect is typically seen after the steroid has been used for more than 4 weeks. The gynecomastia does reverse when the steroid is discontinued.

Over dose

Over dose with Testosterone Cypionate is very rare. The drug is usually administered as an injection. If excess dose is injected, there are no acute side effects but the individual may feel sick for a few weeks. Depending on the dose injected, a visit to the hospital or a physician’s office would not be a bad idea.

Dosage

In clinical medicine, Testosterone Cypionate is administered as an injection. The oily suspension is injected only into the muscles. Testosterone Cypionate is available in two strengths 100mg/ml and 200 mg/ml. It is only made for intramuscular injection. The drug can be injected into the buttock area once every 7-12 days. The majority of the Testosterone Cypionate is bound to protein and only 2% is free. The drug is supposed to be injected once a week, but there are some bodybuilders who do inject it every other day.    

This is not recommended and can lead to the formation of abscess, sores and skin infections.

The injection site needs to be rotated if the injections are to be continued for a long time. The oily suspension should not be injected into the arms or the abdomen. The dose of Testosterone Cypionate ranges from 50mg-400mg/week, depending on the condition being treated. Bodybuilders tend to inject the higher amount of the drug- 200mg-400mg/week. The drug is then slowly absorbed into the blood stream over the next few days.

Control

Testosterone Cypionate is a controlled substance and classified under class 3 under the Controlled Substance Act. It is only available in the USA with a physician’s prescription. Possession, distribution or sell of this anabolic steroid is considered illegal.

Detection

Anytime an oily suspension of drug is used, the drug does tend to remain in the body for a long time. Testosterone Cypionate and its metabolites can be detected in the urine for as long as 2-3 weeks after the last injection. Because of this long duration in the body, most bodybuilders prefer to take the drug during the off season.

Availability

The majority of bodybuilders get their Testosterone Cypionate from the black market. In the USA the original pharmaceutical product is well controlled and not available for sale. Generic forms of the steroid have been made in Japan, Australia, Mexico, Spain, Brazil and Thailand is all available.
 
Most bodybuilders use between 200-1000mg/week and a vial of 400mg in 2 ml can cost anywhere from $20-$40. this can easily amount to $200 per month depending on the dose.
 
However, like all things in cyberspace the purity and quality of the product is always in question. And fakes products are plentiful

Alternative designation

testo, testosteron, testosterone, test, cypionax, cypionax br, testabol, testabol depot, cytex, cytex 250, cytex thaiger, cypioject, cypionat, cypionate 200, cypionate 200 maxpro, cypionat la, cypionate la, testex, testex elmu, testex elmu prolongatum, testex elmu prolongat, testosterone cypionate injection, x-cypionat, t-cypionat, Andro-Cyp, Androgen-860, Andronate, Biosterone, Ciclostrone, C.P.T., Cyclotestex, Cyclovirex, depAndro, Depostomead, Depo-Testosterone, Depotrone, Depovirin, Dep-Test, Dep-Testosterone, Devirin, D-Test, Durandro, Jectatest, Malogen, Cyp., Neo-Testosterona depositum, Pentosteron, Pertestis depositum, Proterona, Retar-Gen A, Sadiferol, Supertest, Tardotest, Testa-C, Testergon, Testex Leo prolongatum, Testobios depositum, Testodrin prolongatum, Testo-Endo, Retardo, Testoject, Testorit-Deposito, Testorolland-Depot, Testosterone Deposito, Testosterone Lusofarmaco Depositum, Testosterone Retard, Testovister-Depot, Testro-Depo, Testromed-P.A., T-Ionate, Viridepon depot

L'articolo Testocyp Alpha Pharma [250mg/1ml] proviene da Steroids.TO.

Testosterone also has the ability to cause a mild increase in the production of red blood cells by stimulating the synthesis of EPO from the kidney. This results in an increase in the red blood cells and hence an increase in the oxygen carrying capacity.

When testosterone is taken for prolonged periods, it inhibits the release of Gonadotropins from the pituitary gland through a negative feedback mechanism. At large doses, it can even inhibit spermatogenesis.

Testosterone also has the ability to cause a mild increase in the production of red blood cells by stimulating the synthesis of EPO from the kidney. This results in an increase in the red blood cells and hence an increase in the oxygen carrying capacity.

When testosterone is taken for prolonged periods, it inhibits the release of Gonadotropins from the pituitary gland through a negative feedback mechanism. At large doses, it can even inhibit spermatogenesis.

Dose

Testosterone enanthate (Delatestryl) is only slowly released after an intramuscular injection and that is why it should not be taken more than 1-2 times a month. The formulation comes as an esterified preparation of testosterone which is only meant to be administered by an intramuscular injection. The esterification of the testosterone increases the duration of action of the testosterone. The preparation comes in a colorless to mild yellow suspension of sesame oil. For medical uses, a dose of 250-500mg is used once a month.

Indications

Delatestryl is indicated in the treatment of conditions where testosterone is either deficient or absent. These conditions include:
     
primary hypogonadism- where the testes has been injured and fails to make the testosterone
Hypogonadism due to failure of the pituitary gland to release of Gonadotropins.
delayed puberty
In females with breast cancer, testosterone may help block the effects of estrogen and prevent further spread. It is an option instead of surgical removal of the ovaries.
 
In most cases of testosterone deficiency, therapy is required for a long time until the secondary sexual characteristic have been developed and the growth is adequate.

Duration

The treatment of all individuals with testosterone enanthate depends on age, sex, diagnosis and the response to treatment- and the onset of adverse effects. In general, the drug is well tolerated when prescribed as recommended. Delatestryl should always be injected in the buttock muscles and not simply underneath the skin. The injection site should be rotated to prevent abscess formation.  Another option is to inject the drug on the outside of the thigh. The drug should never be administered intravenously.
 
The dose of testosterone enanthate should not exceed more than 1000 mg per month because the drug has prolonged activity. It is extremely rare to give this drug once every two weeks. The drug should always be inspected before injection. It is usually a colorless-yellow suspension which is clear. Any particulate matter or clumping indicates that the product is expired or inactive. The duration of treatment varies from 4-6 months.
 
The drug should be stored at room temperature.

Bodybuilders

A lot of bodybuilders use Delatestryl during the off season. The drug stays in the body for a long time and it is advisable not to use it during the active sports season. The drug definitely has anabolic and androgenic properties. However, the effects of the drug are not immediate and may take at least 3-4 weeks to become evident. Many bodybuilders also use other anabolic hormones like GH/thyroxin in combination.

Because testosterone is also converted to estrogen in the fatty tissues, many bodybuilders develop breast enlargement and retain water. The dose used to increase muscle mass and strength is about 250-1000 mg/week. However, at the higher doses the drug has potent side effects and it is highly recommended that all beginners start off with the low dose.

The increase in protein mass is gradual but does occur. Because the steroid also stimulates red blood cell production, many bodybuilders also notice that they have an increased capacity to perform under intense exercise conditions. Testosterone enanthate is preferred by most bodybuilders because it is readily available and has a number of benefits. It promotes good health, increase exercise performance and leads to a positive nitrogen balance. There are reports that it also selectively decreases fat and increases muscle mass. Recent studies from the World sports agencies indicate that this particular drug can boost performance, increase lean muscle mass and still not be detected in the urine within the first few weeks. Even when the anabolic effects are not obvious, most individuals do notice an increase in strength. Sometimes the water retention can be quite dramatic and some individuals do take a diuretic pill to remove it. To prevent the breast enlargement, testosterone enanthate is cycled with drugs like Arimidex or Tamoxifen. Most individuals take the testosterone for 4-6 weeks and then stop for a few weeks. During this wash out phase, one may use Arimidex.

Women

All testosterone analogues have the potential to cause virilizing effects when the duration of use is prolonged. In females, these virilizing signs may be deepening of voice, excessive hair growth, irregular menstrual cycles, mood alterations and clitoral enlargement. It is recommended that at the first sign of virilizing symptoms the drug should be stopped. The reason for this is that some of the virilizing signs may not be reversible even after discontinuation of the steroid.

Side effects

Like all anabolic steroids, testosterone enanthate has a few side effects. These side effects are generally mild and well tolerated. The majority of individuals do see some side effects after 3-4 months of therapy. The most common side effects include:
irregular menstrual cycles
virilizing effects
deepening voice
clitoral enlargement
gynecomastia
painful penile erections
hair loss, acne oily skin
retention of body water
nausea, vomiting, jaundice
liver cancer (rare)
mental changes, depression, headaches, anxiety,
increased serum cholesterol
While most of these side effects are reversible, the breast enlargement and some virilizing effects are not. The concomitant use of estrogens to diminish the side effects of virilization is not always helpful.
In children the use of testosterone must be strictly monitored. It can accelerate bone maturation but does not increase compensatory linear growth – which results in abnormal body distortion in anatomy- esp. the jaw and face.

Warnings

The drug should be used very cautiously in individuals with:
     
breast cancer and hypercalcemia
liver dysfunction
prostate cancer
heart problems
 
There have been isolated reports of individuals developing a dry cough, breathing difficulties after injection with testosterone enanthate. This has been linked to the oil based preparation or a contaminant in the formulation.
 
All individuals who use testosterone should have their liver enzymes and blood hematocrit regularly checked to ensure that they are within normal limits.

Legal

Delatestryl is classified as a class 3 drug under the controlled substance act. In the USA, it is only available with a physician’s prescription.

Detection

Testosterone enanthate has a very long half life in the body. For this reason it is also detected in the urine long after it has been discontinued. Current techniques of testing can identify testosterone or its metabolites in the urine at least 3-4 weeks after the drug has been stopped. Infact, the testing has even gone beyond urine testing. If excessive use of the testosterone is suspected, one can even detect traces of the testosterone in the hair 2-4 months after the drug has been stopped.
 
However, one should know that the testing today for testosterone enanthate is not perfect. About 50% of individuals who take this steroid are missed based on the testosterone/epitestosterone ratios.

Cost

The legal testosterone enanthate is quite difficult to get hold off. The majority of bodybuilders get their testosterone from the black market. Generic testosterone formulations made in Europe and Mexico are widely available. The drug is not cheap and a vial of 250 mg can cost anywhere from $10-$20. In the last 2 decades, the increasing control of these drugs by the DEA has led to unscrupulous dealers selling fake or counterfeit products. So in the end, it is always buyer beware.

Alternative designation

testo, testosteron, testabol, testosterone aburaihan, testosterone enanthate 250, testabol enanthate, testosterone, test, testosteron enanthat, testosterone enanthat, testosterone enanthate, testosteron enantat, testosterone enantate, enanject, galenika, testosterone depo, testosteron depo, testosteron depo galenika, testosterone enanthate norma, enanthat norma, testosteronum prolongatum, testosteron prolongatum, testoviron, testoviron 250, testoviron maxpro, x-prolongat, t-enanthat, delatestryl, Androgyn L.A., Andro L.A.200, Androtardryl, Andryl, Anthatest, Arderone, Atlatest, Delatest, Delatestryl, Depo-Testro-Med, Depotestrone, Despavir, Dura-Testate, Dura-Testosterone, Enarmon-Depot, Enosteron, Ergoteston, Everone, Exten Test, Malogen L.A., Malogex, Orquisteron-E-Depot, Primoniat-Depot, Primotest-Depot, Primoteston-Depot, Proviron-Depot, Reposterone, Repo-Test, Repo-Testro Med, Retandros-200, Span-Test, Tesone L.A., Testahome-Depot, Testanate, Testanthate, Testate, Testinon Depot 250 mg, Testisan-Depo, Testo-Enant, Testofort, Testone L.A., Testoron retard, Testosteron depo, Testosteron-Depot-Amp., Testostérone, Théramex, Testosteronum Prolongatum, Testostroval, Testoviron-Depot, Testrin-P.A., Testrolen

L'articolo Testobolin Alpha Pharma [250mg/1ml] proviene da Steroids.TO.